Status:

COMPLETED

Effect of DHA on Proinflammatory Cytokines Including Platelets Activating Factor (PAF) in Preterm Neonates

Lead Sponsor:

Ain Shams University

Conditions:

Neonatal Disease

Eligibility:

All Genders

1-28 years

Phase:

NA

Brief Summary

The purpose of this study is to determine whether docosahexaenoic acid is effective in the prevention or reducing severity of necrotizing enterocolitis in preterm/low birth weight neonates.Necrotizing...

Detailed Description

Inclusion criteria: Patients are eligible for inclusion if they meet the following criteria: Preterm neonates having a gestational age equal or less than 32 weeks at birth, admitted in Ain Shams Uni...

Eligibility Criteria

Inclusion

  • Preterm neonates having a gestational age equal or less than 32 weeks at birth, admitted in Ain Shams University NICU'S.
  • Weight (less than or equal 1.500 KG) Clinically stable to begin enteral feeding All Genders (Male, Female) Written informed consent by parents Sepsis will not be considered as exclusion criteria (according to SNAP 11; this score considers six physiologic variables such as blood pressure, temperature, the Po2/Fio2 ratio, serum PH, seizures and urine output, Töllner score (table 3) and Rodwell score

Exclusion

  • Persistent bleeding at any level. Receiving medication to avoid coagulation. Persistent vomiting. Gastrointestinal malformations. Mother taking Omega-3 supplements and planning to breastfed.

Key Trial Info

Start Date :

September 21 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2021

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04746885

Start Date

September 21 2017

End Date

January 1 2021

Last Update

February 10 2021

Active Locations (1)

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1

Ain Shams University

Cairo, Egypt, 11566