Status:

UNKNOWN

Nitazoxanide in Prevention of Secondary Spontaneous Peritonitis

Lead Sponsor:

Tanta University

Conditions:

Spontaneous Bacterial Peritonitis

Eligibility:

All Genders

21-65 years

Phase:

PHASE3

Brief Summary

the study is to evaluate the possible efficacy and safety of nitazoxanide as an adjuvant therapy in the secondary prevention of SBP in patient with cirrhosis.

Detailed Description

due to high recurrence rate of spontaneous bacterial peritonitis , we will study and evaluate the possible efficacy and safety of NTZ as an adjuvant therapy in the secondary prevention of SBP in patie...

Eligibility Criteria

Inclusion

  • Patients aged 21 - 65 years old with cirrhosis and ascites who had at least one previous confirmed episode of spontaneous bacterial peritonitis.

Exclusion

  • Exclusion criteria included active gastrointestinal bleeding Hepatic encephalopathy (\>grade 2) Hepatocellular carcinoma (HCC) or other malignancies Allergy to used medications.

Key Trial Info

Start Date :

March 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2022

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04746937

Start Date

March 1 2021

End Date

May 1 2022

Last Update

February 10 2021

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