Status:

COMPLETED

Eye Gaze Strategies During Facial Emotion Recognition in Neurodegenerative Diseases: Links With Neuropsychiatric Disorders (EYE-ToM Study)

Lead Sponsor:

Centre Hospitalier Princesse Grace

Collaborating Sponsors:

Association de Recherche Bibliographique pour les Neurosciences

Conditions:

Alzheimer's Dementia

Parkinson Disease(PD)

Eligibility:

All Genders

45+ years

Brief Summary

It is commonly admitted that social cognition impairment, like deficit in facial emotion recognition or misinterpretation of others' intentions (Theory of Mind), are associated with social behavior di...

Eligibility Criteria

Inclusion

  • Hospitalized or coming to perform a consultation, for whom an Eye-Tracking examination is indicated as part of routine care.
  • Sufficient written and oral expression in French.
  • Written informed consent signed by the patient.
  • For the control group: No cognitive impairment (non pathological MMSE (according to age, gender and socio-cultural level), no neurological history, and no psychiatric history (especially anxiety and depressive disorders).
  • For the FTD group: Patient diagnosed according to revised Rascovsky et al. 2011., no neurological history (excepted diagnosed FTD), and no psychiatric history (excepted those related to diagnosed FTD).
  • For the AD group: Patient diagnosed according to DSM-IV-TR criteria, no neurological history (excepted diagnosed AD), and no psychiatric history (excepted those related to diagnosed AD).
  • For the PD group: Patient diagnosed according to NINDS criteria, no neurological history (excepted diagnosed PD), and no psychiatric history (excepted those related to diagnosed PD).

Exclusion

  • General anaesthesia within 3 months.
  • Ophthalmological problems preventing a video-oculography examination.
  • Oculomotor disorders such as "fixation disorders" or "ocular tracking disorders".
  • Cognitive disorders of the type: visual agnosia, visuo-spatial disorder, visuo-perceptual disorder or aphasia.
  • History of stroke.
  • History of alcohol or drug abuse.

Key Trial Info

Start Date :

July 1 2015

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 1 2020

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT04748263

Start Date

July 1 2015

End Date

November 1 2020

Last Update

February 10 2021

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