Status:
TERMINATED
Impaired Glucose Tolerance and Cognition in MS
Lead Sponsor:
University of Virginia
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18-59 years
Brief Summary
This is a pilot study to compare cognitive performance in two groups of subjects with multiple sclerosis; those with normal glucose tolerance and those with impaired glucose tolerance. The study consi...
Detailed Description
Investigators plan to recruit 100 compliant patients with relapsing-remitting MS who are willing to come fasting for an oral glucose tolerance test to determine the relationship between glucose tolera...
Eligibility Criteria
Inclusion
- Ability to provide informed consent
- Diagnosis of Clinically Isolated Syndrome (CIS) or Relapsing Remitting Multiple Sclerosis (RRMS) confirmed by McDonald 2010 criteria
- EDSS \< 6.5 at time of visit
Exclusion
- Diabetes type I or II
- use of glucose regulating medications
- fasting blood glucose of \> 126 mg/dl
- known cardiac or respiratory disease
- morbid obesity (BMI \>40)
- steroid exposure within 4 weeks of enrollment
- pregnancy or current use of hormone replacement therapy
Key Trial Info
Start Date :
January 6 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2020
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT04748302
Start Date
January 6 2020
End Date
April 1 2020
Last Update
February 10 2021
Active Locations (1)
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1
University of Virginia
Charlottesville, Virginia, United States, 22903