Status:

COMPLETED

Lipid Kinetics of Patients With Pneumonia

Lead Sponsor:

Konya Numune Hospital

Conditions:

Gram-negative Bacteria

Lipid Metabolism

Eligibility:

All Genders

18-85 years

Brief Summary

Nonfermenting Gram-Negative Bacilli (NFGNB) are aerobic, non-motile, non-lactose fermenting, oxidase-negative, catalase-positive coccobacilli that pose a serious threat to critically ill patients. Pri...

Detailed Description

This prospective study was performed in adult intensive care unit (ICU) patients. They were intubated endotracheally and received mechanical ventilation (MV) treatment for at least 48 hours in Konya N...

Eligibility Criteria

Inclusion

  • ICU Patients of 18 years of age and above, with clinical suspicion of VAP as defined in the American Thoracic Society (ATS) guidelines and a simplified version of Clinical Pulmonary Infection Score (CPIS)\> 6, with significant NFGNB growth in respiratory cultures and with no signs and symptoms of infection at the time of admission, were included in the study.

Exclusion

  • Patients with chronic inflammatory disease, hepatic dysfunction, active tuberculosis, malignancy, malnutrition, severe immunosuppression (i.e., neutropenia, HIV positive, organ transplant, having received immunosuppressants or used ≥ 20 mg/day prednisone for two or more weeks in the preceding three months), those that within 72 hours since being included in the study had any extrapulmonary infection other than VAP, as well as those whose respiratory cultures presented bacterial agents other than NFGNB and fungal agents were not included in the study.

Key Trial Info

Start Date :

May 25 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2020

Estimated Enrollment :

131 Patients enrolled

Trial Details

Trial ID

NCT04748432

Start Date

May 25 2019

End Date

December 31 2020

Last Update

March 12 2024

Active Locations (1)

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Konya Numune Hospital

Konya, Turkey (Türkiye), 42060