Status:

COMPLETED

Vaginal Progesterone 400mg v.s 200mg for Prevention of Preterm Labor in Twin Pregnancies

Lead Sponsor:

Ain Shams University

Conditions:

Twin Pregnancy With Antenatal Problem

Eligibility:

FEMALE

18-40 years

Phase:

PHASE4

Brief Summary

It is already known that the risk of preterm labor in twin pregnancy before 37 week is 8-9 fold higher compared to singletons, and progesterone supplementation can decrease the incidence of preterm la...

Eligibility Criteria

Inclusion

  • Primigravidae
  • Twin pregnancies at gestational age 14 week.
  • Cervical length more than 2 cm (because if 2cm or less they will undergo cervical cerclage.)

Exclusion

  • Polyhydramnios
  • Anemia
  • Twins with congenital malformation
  • Twin to twin transfusion
  • Medical diseases as diabetes mellitus, hypertension and systemic lupus erythematosis
  • Previous cervical surgery
  • High order pregnancy (triples or more)

Key Trial Info

Start Date :

January 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2020

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04748562

Start Date

January 1 2020

End Date

December 1 2020

Last Update

February 10 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Ain Shams University Maternity hospital

Cairo, Egypt