Status:

RECRUITING

Bilateral Essential Tremor Treatment With Gamma Knife

Lead Sponsor:

Université de Sherbrooke

Collaborating Sponsors:

University Health Network, Toronto

Conditions:

Essential Tremor

Eligibility:

All Genders

18+ years

Phase:

PHASE2

PHASE3

Brief Summary

Combined Phase II/III, multi-center, prospective, single-blinded trial. Ten (10) patients with essential tremor who previously underwent successful and uncomplicated GK thalamotomy for essential trem...

Eligibility Criteria

Inclusion

  • Patients must be ≥ 18 years
  • The patient has a primary diagnosis of ET or ET plus confirmed by a movement disorder neurologist;
  • The patient previously underwent a GK thalamotomy (\> 12 months ago);
  • The tremor on the untreated side negatively impacts the patients' quality of life;
  • The patient wants treatment of the contralateral side.

Exclusion

  • Clinically relevant gait and/or balance impairment (e.g. wide-based, more than 2 falls/months, wheelchair, walker, cane use);
  • Clinically relevant speech impairment (e.g. impairment of intelligibility);
  • Inability to comply with the follow-up schedule;
  • Refusal of the treating physician.

Key Trial Info

Start Date :

June 8 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2026

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04748640

Start Date

June 8 2021

End Date

October 1 2026

Last Update

November 17 2021

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Toronto Western Hospital, University Health Network

Toronto, Ontario, Canada, M5T 2S8

2

CIUSSS de l'Estrie-CHUS - Hôpital Fleurimont

Sherbrooke, Quebec, Canada

Bilateral Essential Tremor Treatment With Gamma Knife | DecenTrialz