Status:

RECRUITING

A Natural History Study of Children and Adults With Olfactory Neuroblastoma

Lead Sponsor:

National Cancer Institute (NCI)

Conditions:

Olfactory Neuroblastoma

Esthesioneuroblastoma

Eligibility:

All Genders

3-120 years

Brief Summary

Background: Olfactory neuroblastoma (ONB) is a rare cancer. It grows from tissue in the upper part of the nose cavity, related to the sense of smell and can affect a person s sense of smell. Research...

Detailed Description

Background: Olfactory neuroblastoma (ONB), also known as esthesioneuroblastoma, is a malignant tumor of the nasal cavity believed to arise from the olfactory epithelium. ONB is rare, with a reported ...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • Subjects must also enroll on NCI Protocol 18-DC-0051: "Biospecimen Procurement for NIDCD Clinical Protocols".
  • Subjects with histologically documented olfactory neuroblastoma.
  • Age \>= 3 years old.
  • Ability of subject to understand and the willingness to sign a written consent document
  • EXCLUSION CRITERIA:
  • Pregnant women are excluded from this study because of more than minimal risk activities (imaging studies with contrast, biopsies) pertaining to enrollment.

Exclusion

    Key Trial Info

    Start Date :

    June 2 2022

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 31 2029

    Estimated Enrollment :

    525 Patients enrolled

    Trial Details

    Trial ID

    NCT04755205

    Start Date

    June 2 2022

    End Date

    December 31 2029

    Last Update

    January 8 2026

    Active Locations (1)

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    National Institutes of Health Clinical Center

    Bethesda, Maryland, United States, 20892