Status:

RECRUITING

Study Roles of Heavy Metals and Essential Metal Dyshomeostasis in Pulmonary Arterial Hypertension Patients

Lead Sponsor:

Jiapeng Huang

Conditions:

Pulmonary Hypertension

Metal Poison

Eligibility:

All Genders

18+ years

Brief Summary

Investigators plan to recruit 50 PAH patients from UofL PAH Clinic, with various degrees of severity (25 intermediate risk patients and 20 high risk patients) and 10 age and gender matched controls. P...

Detailed Description

Exposures to heavy metals such arsenic, lead, cadmium have been linked to increased incidence of cardiovascular disease (CVD). However, current studies suffer from multiple drawbacks, most studies wer...

Eligibility Criteria

Inclusion

  • All patients with the diagnosis of pulmonary hypertension
  • Agree to the study protocol
  • Healthy volunteers
  • Age, gender matched controls

Exclusion

  • Younger than 18 years
  • Refusal to participate

Key Trial Info

Start Date :

December 2 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2029

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT04756076

Start Date

December 2 2020

End Date

December 31 2029

Last Update

May 30 2025

Active Locations (1)

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1

University of Louisville Health

Louisville, Kentucky, United States, 40202