Status:

COMPLETED

Vancomycin Dose Adjustments Comparing Trough Levels to The AUC/MIC Method Using a Bayesian Approach in a Hospitalized Adult Population

Lead Sponsor:

CR-CSSS Champlain-Charles-Le Moyne

Conditions:

Vancomycin

Adult

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This pilot study is a prospective, randomized, controlled, open-label trial to assess the feasibility of a randomized controlled trial of sufficient quality that would assess the efficacy and safety o...

Eligibility Criteria

Inclusion

  • At least 18 years of age;
  • Hospitalized patients
  • Suspected or confirmed infection;
  • Anticipated IV vancomycin treatment for 24 hours or more.

Exclusion

  • Patients with renal replacement therapy (peritoneal dialysis, continuous renal replacement therapy or hemodialysis);
  • Treatment of vancomycin in continuous infusion;

Key Trial Info

Start Date :

March 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 6 2021

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT04756895

Start Date

March 1 2021

End Date

August 6 2021

Last Update

September 10 2021

Active Locations (1)

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1

Charles-Le Moyne Hospital

Greenfield Park, Quebec, Canada, J4V 2H1