Status:
COMPLETED
S-ketamin Premedication in Pediatric EENT Surgery
Lead Sponsor:
Eye & ENT Hospital of Fudan University
Conditions:
Emotions
Separation Anxiety
Eligibility:
All Genders
2-12 years
Phase:
EARLY_PHASE1
Brief Summary
We aim to investigate the effects of premedication (intranasal or intravenous administration) of s-ketamin, dexmedetomidine, and combination for premedication in children undergoing ENT surgery.
Detailed Description
Three hundred children aged between 2 and 12 years were randomly allocated to one of five groups: 0.3 μg/kg intravenous injection s-ketamin; 0.5 μg/kg intravenous injection s-ketamin; 2 μg/kg intranas...
Eligibility Criteria
Inclusion
- After obtaining the informed consent from their parents or proxies, the children aged 2 to 12 years, scheduled for elective ENT surgery, of American Society of Anesthesiologists (ASA) I or II were enrolled in this study.
Exclusion
- Congenital heart diseases, congenital dysplasia, obstructive sleep apnea syndrome, upper respiratory tract infection, body mass index (BMI) ≥25, allergy to S-ketamin or dexmedetomidine, and severe liver or kidney disease.
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2022
Estimated Enrollment :
320 Patients enrolled
Trial Details
Trial ID
NCT04757675
Start Date
March 1 2021
End Date
January 1 2022
Last Update
April 27 2022
Active Locations (1)
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1
Eye and ENT Hospital of Fudan University
Shanghai, China