Status:
COMPLETED
Awake Prone Positioning for Non-intubated COVID-19 Patients
Lead Sponsor:
Damanhour University
Conditions:
Prone Position
Coronavirus Disease 2019
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The burden of coronavirus disease 2019 (COVID-19) pandemic is still on a rising course making a great stress on medical resources throughout the world. Although most of COVID-19 patients require non-i...
Detailed Description
A randomised controlled trial design will be adopted to achieve the aim of the current study. In this study 82 adult patients of either sex with a confirmed diagnosis of COVID-19 will be recruited fro...
Eligibility Criteria
Inclusion
- Aged 18-75 years old
- Awake non-intubated spontaneously breathing patients
- Confirmed diagnosis of severe COVID-19; manifesting as dyspnea with respiratory rate ≥ 30 breaths/min, pulse rate ≥ 100 beats/min, oxygen saturation ≤93%, or partial pressure of arterial oxygen (PaO2) to fraction of inspired oxygen (FiO2) ratio ≤ 150 mmHg.
- Positive RT-PCR for SARS-CoV-2 from analysis of nasopharyngeal, oropharyngeal swab, or tracheal secretion specimens and with chest X-ray showing bilateral infiltrations or chest computerized tomographic (CT) images showing exudation or consolidation.
- Requiring supplemental oxygen (nasal cannula, non-invasive CPAP, non-rebreathing face mask)
- Capable of adopting a prone posture independently.
Exclusion
- The presence of any of the following will mean patients are ineligible:
- life-threatening arrhythmias
- Hemodynamic instability (defined as mean arterial pressure \[MAP\] \< 65mm Hg and use of vasopressors to achieve MAP \> 65 mm Hg)
- Altered mental status, intracranial hypertension
- Facial injuries
- Spine or pelvic fractures
- Recent abdominal surgery
- Pregnancy
- Altered mental status and patients needing invasive ventilation.
Key Trial Info
Start Date :
February 20 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 20 2021
Estimated Enrollment :
82 Patients enrolled
Trial Details
Trial ID
NCT04760561
Start Date
February 20 2021
End Date
April 20 2021
Last Update
February 4 2022
Active Locations (1)
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1
Faculty of nursing
Alexandria, Egypt, 02225585888