Status:

WITHDRAWN

Multiple Sessions of Transcranial Direct Current Stimulation in People With Parkinson's Disease

Lead Sponsor:

University of Iowa

Conditions:

Parkinson Disease

Healthy Adult

Eligibility:

All Genders

50-90 years

Phase:

NA

Brief Summary

Parkinson's disease (PD) affects approximately 1 million people in the US, with annual health care costs approaching $11 billion. PD results from a loss of dopamine-producing cells in the brain. This ...

Eligibility Criteria

Inclusion

  • To be eligible to participate in this study, people with PD must meet the following criteria:
  • Adult (50-90 yrs) with a positive diagnosis of Parkinson's disease from a movement disorder specialist
  • On an unchanged regimen of dopaminergic medication for at least the last 3 months
  • Able to independently walk for 6 min
  • Without other severe chronic psychiatric or medical conditions
  • Not taking any psychoactive medications
  • To be eligible to participate in this study, the NH subjects must meet the following criteria:
  • Adult (50-90 yrs)
  • Able to independently walk for 6 min
  • Without any severe chronic psychiatric or medical conditions
  • Not taking any psychoactive medications

Exclusion

  • An individual from either group who meets any of the following criteria will be excluded from participation in this study:
  • Pregnant
  • Known holes or fissures in the skull
  • Metallic objects or implanted devices in the skull/head (e.g., metal plate, deep brain stimulator)
  • Current or previous injuries or surgeries that cause unusual gait
  • A score less than 24 or 17 on the Montreal Cognitive Assessment (MoCA) or telephone-MoCA, respectively
  • Additional exclusion for PwPD:
  • Experience freezing of gait
  • A diagnosis of dementia or other neurodegenerative diseases
  • Additional exclusion for NH subjects:
  • 1\. A diagnosis of dementia or any neurodegenerative diseases

Key Trial Info

Start Date :

August 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2022

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04762823

Start Date

August 15 2021

End Date

January 1 2022

Last Update

June 28 2022

Active Locations (1)

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1

University of Iowa

Iowa City, Iowa, United States, 52242