Status:
ACTIVE_NOT_RECRUITING
Cardiovascular and InflammAging Study
Lead Sponsor:
Green Beat
Collaborating Sponsors:
Medical University of Graz
Conditions:
Aging
Cardiovascular Diseases
Eligibility:
All Genders
55-80 years
Phase:
NA
Brief Summary
Evidence from previous studies supports a strong relationship between fruit and vegetable consumption and reduced cardiac risk. This could be mediated via improvements on blood pressure, platelet func...
Eligibility Criteria
Inclusion
- Post menopausal
- Non-smokers
- BMI 18.5 to 40 kg/m2
- Vegetable intake ≤ 2 servings/ day
- Intake of fruits ≤ 2 servings /day
- Adherence to a 6-week washout period for dietary supplements not ingested for specific medical conditions.
Exclusion
- Age \<55 and \>80 years
- Smokers (or ex-smokers who quit smoking less than 3 years ago)
- Aversion to stop the intake of multivitamins, multiminerals or omega fatty acid supplements
- Subjects with histamine intolerance
- Hypertension, starting with grade 2 according to the classification of the European Society of Hypertension: systolic blood pressure \> 160mmHg, diastolic blood pressure \>100 mmHg
- All medication taken for less than 3 months or with changes on the dosage over the last 3 months and medication for any of the conditions listed below.
- Clinically relevant infectious diseases
- Diabetes mellitus type I and type II
- Rheumatic diseases
- Auto-immune diseases
- Any stents and coronary artery diseases (CAD)
- Cancer patients
- Pregnancy
- Significant lifestyle changes, e.g. changes in diet or physical activity profile
Key Trial Info
Start Date :
September 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04763291
Start Date
September 1 2021
End Date
December 1 2026
Last Update
July 1 2025
Active Locations (2)
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1
Green Beat
Graz, Austria, 8042
2
Otto Loewi Research Center, Section of Physiological Chemistry, Medical University of Graz
Graz, Austria