Status:

COMPLETED

Evaluation of Mangoselect® in Improvement of Exercise/Activity-induced Knee Joint Discomfort in Subjects Suffering From Osteoarthritis Grade I or II

Lead Sponsor:

Fytexia

Conditions:

Osteoarthritis, Knee

Eligibility:

All Genders

50-75 years

Phase:

NA

Brief Summary

The aim of the present investigation is to evaluate the efficacy of Mangoselect®, a mangosteen extract, and of a formulation containing Mangoselect®, in subjects suffering from activity/exercise-induc...

Eligibility Criteria

Inclusion

  • Physically active volunteers
  • BMI 22-29.9 kg/m2
  • Declaring knee joint pain during and/or after activity/exercise
  • Joint knee pain rated of at least 4 cm on a 10 cm VAS following activity/exercise
  • Diagnosed osteoarthritis grade I or II according to Kellgren-Lawrence classification

Exclusion

  • Diagnosed inflammatory joint disorder or osteoarthritis grade III or more according to Kellgren-Lawrence classification
  • Currentlu chronically taking pain killer drugs or dietary supplement or intra-articular treatment 3 months before selection
  • Anemia
  • Subjects with knee/joint surgery/replacement in the past 10 years
  • Significant injury of the studied knee joint 12 months before selection
  • Unable to carry out functional tests and/or questionnaires
  • Currently participating or having participated in another clinical trial in the 3 previous months
  • Pregnant women and women positive at Beta-HCG serology test
  • Any condition that the investigator believes would interfere with the ability to provide inform consent, or comply with study instructions, or confound the interpretations of the study results, or put the volunteer at undue risk
  • Allergy to one of the component of the supplements

Key Trial Info

Start Date :

March 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 26 2023

Estimated Enrollment :

95 Patients enrolled

Trial Details

Trial ID

NCT04765189

Start Date

March 1 2021

End Date

October 26 2023

Last Update

December 5 2023

Active Locations (1)

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1

UCAM (Universidad Catolica San Antonio de Murcia)

Murcia, Spain