Status:

COMPLETED

The Menopause After Cancer Study

Lead Sponsor:

University College Dublin

Collaborating Sponsors:

Irish Cancer Society

Big Health Inc.

Conditions:

Menopause

Cancer

Eligibility:

FEMALE

18+ years

Phase:

PHASE2

Brief Summary

This study will recruit women with vasomotor symptoms of menopause and a prior cancer diagnosis, for whom conventional menopausal hormone therapy (MHT) is contraindicated for any reason. This study wi...

Detailed Description

Patients who are eligible and provide informed consent will be enrolled into this single arm study. Patients will be prescribed non-hormonal pharmacotherapy tailored to the timing of their predominant...

Eligibility Criteria

Inclusion

  • Females over 18 years of age at the time of recruitment and onboarding.
  • Vasomotor symptoms of menopause
  • Previous or current cancer diagnosis
  • Conventional menopausal hormone therapy contraindicated for any reason
  • Can speak and read English proficiently
  • Competent using the internet and has access to smartphone or similar device

Exclusion

  • ECOG performance status \>3
  • Use of study medications to manage menopausal symptoms in the preceding 6 months
  • Use of CBT for insomnia in the preceding 6 months
  • Any contraindication to study medications
  • No internet access or competency issue with internet use
  • Unable to complete questionnaires or give informed consent
  • Current major mental illness

Key Trial Info

Start Date :

June 21 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 30 2022

Estimated Enrollment :

205 Patients enrolled

Trial Details

Trial ID

NCT04766229

Start Date

June 21 2021

End Date

November 30 2022

Last Update

January 6 2023

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Mater Misericordiae University Hospital

Dublin, Ireland

2

St. Vincent's University Hospital

Dublin, Ireland