Status:

COMPLETED

A Clinical Study of SHR8554 Injection for the Treatment of Pain After Abdominal Surgery.

Lead Sponsor:

Jiangsu HengRui Medicine Co., Ltd.

Conditions:

Pain

Eligibility:

All Genders

18-65 years

Phase:

PHASE3

Brief Summary

The primary objective is to evaluate the analgesic efficacy of IV SHR8554 compared with placebo and morphine in patients with acute postoperative pain following abdominal surgery

Eligibility Criteria

Inclusion

  • Able and willing to provide a written informed consent
  • Subjects requiring elective general anesthesia abdominal surgery
  • Conform to the ASA Physical Status Classification

Exclusion

  • Subjects with a history of difficult airway
  • Subjects with a history of reflux esophagitis
  • Subjects with a history of mental illness
  • Subjects with poor blood pressure control
  • Transcutaneous oxygen saturation (SpO2) \<90%
  • Random blood glucose ≥11.1mmol/L
  • Subjects with abnormal liver function
  • allergies to opioids and other medications that may be used during the trial
  • Pregnant or nursing women

Key Trial Info

Start Date :

March 3 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2021

Estimated Enrollment :

528 Patients enrolled

Trial Details

Trial ID

NCT04766463

Start Date

March 3 2021

End Date

November 1 2021

Last Update

July 6 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Union Hospital Affiliated to Tongji Medical Collage Huazhong University of Science and Technology

Wuhan, Wuhan, China, 430021