Status:
COMPLETED
Bonds Between Circulating Tumoral ADN (ctDNA) and the Development of Peritoneal Carcinomatosis for Patients Under PIPAC
Lead Sponsor:
Institut de Cancérologie de Lorraine
Conditions:
Peritoneal Carcinomatosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
PIPADN is a pilot monocentric, study with a total duration of 42 months. The purpose of this study is to describe the variation of plasma ctDNA concentration between the 1st and the 3rd PIPAC session ...
Eligibility Criteria
Inclusion
- Age ≥ 18 years old
- WHO 0 to 2
- Patient with cancer in the form of peritoneal carcinosmatois not eligible for cytoreduction surgery
- A histological diagnosis of the primary tumor or peritoneal carcinomatosis is essential.
- Patient with an indication for PIPAC for any reason (whether as part of a clinical research protocol or not). Patients with prior treatment with PIPAC are eligible.
- Patients with abdominal metastases or a single metastasis regardless of location (oligometastasis).
- For patients of childbearing age need for an effective method of contraception
- Informing patients and obtaining informed consent, dated and signed.
- Patient affiliated with a social security scheme
Exclusion
- Age \< 18 years old
- WHO \> 3
- Patient who may benefit from cytoreduction surgery
- Patient with a contraindication to PIPAC
- Extra peritoneal disease with the exception of oligometastatic disease
- Persons deprived of liberty or under guardianship (including curatorship)
- Impossibility to undergo the medical follow-up of the trial for social, geographical or psychological reasons.
- For patients of childbearing age without an effective method of contraception
- Woman who is pregnant, likely to be pregnant, or breastfeeding
Key Trial Info
Start Date :
January 11 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 7 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04766502
Start Date
January 11 2022
End Date
January 7 2025
Last Update
July 24 2025
Active Locations (1)
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1
Institut de Cancérologie de Lorraine
Vandœuvre-lès-Nancy, France