Status:
UNKNOWN
The Pharmacokinetics of Silver Diamine Fluoride (SDF) in Healthy Children
Lead Sponsor:
University of Malaya
Conditions:
Dental Caries in Children
Eligibility:
All Genders
4-10 years
Phase:
NA
Brief Summary
This study focus on the pharmacokinetic characteristic of silver diamine fluoride (SDF) in healthy children. All of the children received treatment for the decayed teeth in the same way. A medication ...
Detailed Description
This research aims to determine the pharmacokinetics characteristics of silver and fluoride following topical application of Silver Diamine Fluoride (SDF) in healthy children. The use of Silver Diamin...
Eligibility Criteria
Inclusion
- 1\. Healthy children aged between 4 to 10 years old
- With at least one decayed primary tooth without clinical signs or symptoms suggesting reversible or irreversible pulpitis.
- Radiographically the deepest layer of caries lesion does not encroach on pulp, and inter-radicular supporting structures appear normal
Exclusion
- Children aged below 4 years and above 10 years
- Healthy children aged between 4 to 10 years old
- Do not have decayed teeth
- The decayed tooth with clinical signs or symptoms suggesting reversible or irreversible pulpitis
- Radiographically the deepest layer of caries lesion does encroach on pulp, and inter-radicular supporting structures appear abnormal
- No consent and permission to join the study
- Taking medications/over the counter medications/supplements
- Known allergy to silver or fluoride
- Presence of ulcer in the mouth which has not heal completely
- Presence of at least one tooth treated with silver fillings or stainless steel crown.
- Presence of at least one tooth filled with a material that contains glass particles known as glass ionomer within a year before this research.
- Children with medical problems
Key Trial Info
Start Date :
July 3 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 26 2021
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT04766775
Start Date
July 3 2020
End Date
November 26 2021
Last Update
March 3 2021
Active Locations (1)
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1
University of Malaya
Kuala Lumpur, Kuala, Malaysia, 50603