Status:

COMPLETED

Incidence of VAP in Patients With Severe COVID-19

Lead Sponsor:

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Conditions:

Ventilator Associated Pneumonia

Covid19

Eligibility:

All Genders

18+ years

Brief Summary

Combined retrospective and prospective cohort study to evaluate the incidence of microbiologically confirmed VAP in mechanically ventilated patients with COVID-19. In the retrospective part, microbiol...

Detailed Description

Ventilator-associated pneumoniae (VAP) is the most common infection acquired in the intensive care unit (ICU). To date, there is no diagnostic gold standard for VAP, and its diagnosis is based on scor...

Eligibility Criteria

Inclusion

  • Retrospective part all patients admitted to the ICU for COVID-19-related respiratory failure since the beginning of the pandemics will be included.
  • Prospective part
  • Age ≥ 18 years
  • Diagnosis of SARS-CoV-2 infection by means of reverse transcription polymerase chain reaction (RT-PCR)
  • Respiratory failure requiring mechanical ventilation
  • mechanical ventilation ongoing for less than 48h

Exclusion

  • Age \< 18 years
  • mechanical ventilation ongoing for more than 48h

Key Trial Info

Start Date :

February 28 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 31 2023

Estimated Enrollment :

323 Patients enrolled

Trial Details

Trial ID

NCT04766983

Start Date

February 28 2020

End Date

January 31 2023

Last Update

March 7 2023

Active Locations (1)

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IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation

Milan, MI, Italy, 20122