Status:
COMPLETED
Regenerative Potential of Advanced Platelet Rich Fibrin and Bioactive Glass (Perioglas®).
Lead Sponsor:
Maharishi Markendeswar University (Deemed to be University)
Conditions:
Chronic Periodontitis
Bone Loss
Eligibility:
All Genders
25-55 years
Phase:
PHASE4
Brief Summary
The aim of this study is to evaluate and compare the regenerative potential of Advanced Platelet Rich Fibrin (A-PRF) and Bioactive Glass (Perioglas®) bone graft in the treatment of intrabony defects i...
Detailed Description
45 sites with vertical intrabony alveolar defects will be selected. These defect sites will be allocated randomly into 3 groups as Group I, Group II and Group III. * Group I will be treated with open...
Eligibility Criteria
Inclusion
- Age: 25 to 55 years.
- Gender: Both males and females will be included in the study.
- Co-operative and motivated patients committed to oral hygiene.
- Patients exhibiting intrabony defects.
Exclusion
- Patients with contraindication to periodontal surgery \& local anesthesia.
- Any systemic disease affecting the bone density and outcome of periodontal therapy.
- Smokers, alcoholics, and patients with other adverse habits.
- Pregnant, nursing and menopausal women.
- Any known allergy/ hypersensitivity to any product used in this study.
- Patients on long-term systemic therapy (antibiotics, anti-inflammatory bisphosphonates, hormonal replacement therapy and any other), taking any drug known to have periodontal implications that may interfere with wound healing.
- Patients taking any anti-platelet and anticoagulant medication.
- Patients who have undergone periodontal treatment within a period of past 1 year.
Key Trial Info
Start Date :
December 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 4 2022
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT04767243
Start Date
December 1 2020
End Date
March 4 2022
Last Update
November 8 2022
Active Locations (1)
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1
Department of Periodontology, M.M. College of Dental Sciences and Research.
Ambāla, Haryana, India, 133207