Status:
COMPLETED
Nitazoxanide as a New Local Adjunctive to Nonsurgical Treatment of Moderate Periodontitis
Lead Sponsor:
Maha Talaab
Conditions:
Periodontitis
Eligibility:
All Genders
20-40 years
Phase:
PHASE2
Brief Summary
The aim of the study was to assess the effect of nitazoxanide delivered subgingivally as thermosensitive hydrogel on the clinical and biochemical outcomes of SRP in patients with moderate periodontiti...
Detailed Description
A randomized, controlled clinical trial in a split-mouth design was conducted on forty patients equally divided between two groups: a control group treated with full mouth scaling and root planing (SR...
Eligibility Criteria
Inclusion
- Patients having probing depth (PD) ≥5 mm.
- Patients having bleeding on probing (BOP) in proximal tooth surface.
- Patients who could maintain an O'Leary plaque index ≤10 proceeded into the study.
Exclusion
- Patients having any systemic disease that may affect the treatment outcomes.
- Smokers.
- Pregnant females.
- Patients receiving contraindicated medications, chemotherapy, or radiotherapy in the previous year.
Key Trial Info
Start Date :
July 20 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2020
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04768530
Start Date
July 20 2019
End Date
April 30 2020
Last Update
February 24 2021
Active Locations (1)
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1
Faculty of Dentistry, Alexandria University
Alexandria, Egypt, 21527