Status:
COMPLETED
Effect of mgso4 on Oxygenation and Lung Mechanics in Morbidly Obese Patients During Bariatric Surgery
Lead Sponsor:
Ain Shams University
Conditions:
Anesthesia
Eligibility:
All Genders
21-60 years
Phase:
PHASE2
Brief Summary
The purpose of this trial is to study the effect of mgso4 infusion on oxygenation and lung mechanics in morbidly obese patients undergoing bariatric surgery
Detailed Description
Background and objectives: morbidly obese patients are characterized by a high prevalence of restrictive lung disease. Respiratory mechanics are significantly altered in obesity. These changes are exa...
Eligibility Criteria
Inclusion
- Patients age between 21-60 years.
- BMI more than 40kg/m2
- Patients with restrictive lung disease(FVC\>70%)
- American society of Anesthesiologists(ASA) physical status II
- No previous abdominal surgery
- Scheduled for laparoscopic bariatric surgery not exceeding 3 hours.
Exclusion
- Patient refusal to participate in the study
- ASA physical status more than II
- patients with heart failure
- Kidney disease
- Patients on antiarrhythmic drugs
- Patients taking beta or calcium channel blockers
- Allergy to study drugs
- Patients with combined restrictive-obstructive lung disease
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 21 2022
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04769440
Start Date
March 1 2021
End Date
February 21 2022
Last Update
July 20 2022
Active Locations (1)
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1
Ain Shams University Hospital
Cairo, Abassia, Egypt, 11591