Status:

COMPLETED

Mindfulness-based Interventions in COPD Patients

Lead Sponsor:

Karl Landsteiner Institute for Lung Research and Pneumological Oncology

Collaborating Sponsors:

University of Vienna

Klinik Ottakring

Conditions:

Chronic Obstructive Pulmonary Disease Exacerbation

Eligibility:

All Genders

40+ years

Phase:

NA

Brief Summary

The purpose of this pilot study is to assess the feasibility of a brief digital mindfulness-based intervention for COPD patients and its effectiveness regarding the reduction of psychological distress...

Detailed Description

Background: Patients with chronic obstructive pulmonary disease (COPD) do not only suffer from somatic symptoms but also from symptoms of anxiety and depression (defined as psychological distress) as...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • spirometry confirmed (FEV1\<80%) COPD diagnosis
  • psychological distress (as assessed by the Hospital Anxiety and Depression Scale): HADS-A ≥ 8 OR HADS-D ≥ 8 OR\*
  • age ≥ 40 years
  • ability to understand German
  • physical and mental capability to attend the intervention, judged by the treating physician
  • life expectancy \> 6 months as judged by treating physician
  • ability to use a smartphone
  • ability not to smoke for the duration of the measurement time points (2-3 hours) (This criterion has been added later, because we learned that this was a problem for some participants. However, smoking during the measurements heavily affects biomarker data and the subjective stress response to a stress induction protocol.)
  • Exclusion Criteria:
  • auditory impairment
  • active asthma diagnosis ("Regardless of your COPD, have you had allergies and asthma in childhood or adolescence and needed medication for them at that time?" If no: No active asthma. If yes: "Is your asthma active and a problem now in addition to your COPD and do you currently need asthma medications because of it?" If no: No active asthma. If yes: exclusion)\*\*
  • any other known severe comorbidities such as heart failure (LVF\<35%), uncontrolled diabetes, concomitant cancer, stroke, unstable coronary heart disease, respiratory failure
  • history of/current severe psychological disorder (e.g. schizophrenia, severe cognitive impairment)
  • current acute exacerbation of COPD
  • any other relevant acute health crisis interfering with the study intervention (e.g. Covid-19)
  • receiving any psychosocial treatment (e.g. psychotherapy)
  • regular other systematic mind-body-practice
  • (\*) When the only exclusion criterion was the HADS, which was often the case, we contacted the participants two months later to screen them again and included them, if they were eligible.
  • (\*\*) We further specified this criterion, as we learned that many patients were told to probably have asthma without them knowing exactly if they had an active asthma diagnosis.

Exclusion

    Key Trial Info

    Start Date :

    April 1 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    March 27 2023

    Estimated Enrollment :

    30 Patients enrolled

    Trial Details

    Trial ID

    NCT04769505

    Start Date

    April 1 2021

    End Date

    March 27 2023

    Last Update

    March 18 2024

    Active Locations (1)

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    Klinik Ottakring

    Vienna, Austria, 1160

    Mindfulness-based Interventions in COPD Patients | DecenTrialz