Status:
TERMINATED
Vascular Dysfunction in Black Individuals: Roles of Nitric Oxide and Endothelin-1
Lead Sponsor:
University of Mississippi Medical Center
Conditions:
Vascular Function
Racial Disparity
Eligibility:
All Genders
18-40 years
Phase:
EARLY_PHASE1
Brief Summary
The research aims of this proposal are: * Specific Aim 1: To test whether an increase in nitric oxide signaling can increase vasodilator responses in young Black individuals. * Specific Aim 2: To tes...
Detailed Description
Studies will be conducted in the Clinical Research and Trials Unit at the University of Mississippi Medical Center. All study visits will follow the same procedures, except for the drug or supplement ...
Eligibility Criteria
Inclusion
- Self-identification of their race and the race of their biological parents as being only Black (i.e., African American) or only White (i.e., Caucasian American)
- Born and raised in the United States
Exclusion
- Mixed races
- Any chronic or ongoing disease
- Prescribed pharmacological treatment
- Smoking or tobacco use
- Obesity (body mass index \> 30 kg / m2)
Key Trial Info
Start Date :
May 27 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 20 2021
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT04770155
Start Date
May 27 2021
End Date
September 20 2021
Last Update
October 31 2023
Active Locations (1)
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1
University of Mississippi Medical Center
Jackson, Mississippi, United States, 39216