Status:

RECRUITING

Genetic Studies of Strabismus, Nystagmus, and Associated Disorders

Lead Sponsor:

Boston Children's Hospital

Collaborating Sponsors:

National Eye Institute (NEI)

Conditions:

Strabismus

Nystagmus, Congenital

Eligibility:

All Genders

Brief Summary

Strabismus (misalignment of the eyes) often runs in families. In this study, the investigators are looking for genetic variants associated with strabismus and nystagmus. Three types of subects will be...

Eligibility Criteria

Inclusion

  • \- Member of a family with at least 3 biological relatives with strabismus. (Both affected and non-affected family members will be enrolled).
  • OR
  • \- Member of a family with at least 1 individual with infantile esotropia. (Both affected and non-affected family members will be enrolled).
  • OR
  • \- Member of a family with at least 1 individual with infantile nystagmus. (Both affected and non-affected family members will be enrolled).

Exclusion

  • paralytic strabismus in affected family members

Key Trial Info

Start Date :

September 3 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2030

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT04770519

Start Date

September 3 2021

End Date

December 1 2030

Last Update

December 12 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115

Genetic Studies of Strabismus, Nystagmus, and Associated Disorders | DecenTrialz