Status:

COMPLETED

Quantification of Exhaled Particles to Identify Airborne Transmission Risks of COVID-19

Lead Sponsor:

Fraunhofer-Institute of Toxicology and Experimental Medicine

Conditions:

Healthy

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

In this study, the aerosols emitted during various respiratory activities will be quantified in healthy subjects. The differences in aerosol size spectrum and number during tidal breathing, speaking, ...

Eligibility Criteria

Inclusion

  • Able and willing to give written informed consent.
  • Healthy male and female subjects, aged 18-80 years.
  • Body mass index between 18 and 35 kg/m2.
  • FEV1 ≥ 80% predicted.

Exclusion

  • Any clinically relevant abnormal findings in physical examination or lung function at screening visit, which, in the opinion of the investigator, may either put the subject at risk because of participation in the study or may influence the results of the study, or the subject's ability to participate in the study.
  • Risk of non-compliance with study procedures.
  • Suspected inability to understand the protocol requirements, instructions and study-related restrictions, the nature, scope, and possible consequences of the study.
  • History of an acute respiratory infection with symptoms such as cough, rhinitis, sore throat, hoarseness or fever, within four weeks prior to the informed consent visit. In case of acute respiratory infection during study participation, the visit may be rescheduled within the allowed time window. Subjects must be asymptomatic for at least 3 days. Re-screening is allowed should the time window be exceeded.
  • History of lung disease including but not confined to COPD, asthma or pulmonary fibrosis.
  • History of latex allergy.

Key Trial Info

Start Date :

March 29 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 20 2021

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04771585

Start Date

March 29 2021

End Date

August 20 2021

Last Update

August 26 2021

Active Locations (1)

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Fraunhofer ITEM

Hanover, Lower Saxony, Germany, 30625