Status:

RECRUITING

Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies

Lead Sponsor:

National Institute of Allergy and Infectious Diseases (NIAID)

Conditions:

Influenza

Respiratory Virus

Eligibility:

All Genders

18-65 years

Brief Summary

Background: Respiratory viruses circulate throughout the year and around the globe. Wearable and sensor devices, like smartwatches, may be able to help monitor infectious diseases. Researchers want t...

Detailed Description

Study Description: Wearable and sensor digital devices have the potential to be important tools in infectious diseases surveillance. In this study, digital devices will be used to evaluate responses ...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • In order to be eligible to participate in this study, an individual must meet all of the following criteria:
  • Able to provide informed consent.
  • Current, recent, or planned enrollment in a respiratory virus challenge study at the NIH Clinical Center.
  • Willing to wear devices as instructed.
  • Willing to participate in monitoring activities as instructed.
  • Willing to have monitoring data stored.
  • Willing to have monitoring data shared with protocol investigators at NIH, University of Washington, and University of Toronto.
  • Willing to have select clinical data from the challenge study such as vital signs, viral shedding, pulmonary function test and/or spirometry results, and clinical symptoms data shared with investigators at University of Washington and University of Toronto.
  • EXCLUSION CRITERIA:
  • An individual who meets any of the following criteria will be excluded from participation in this study:
  • 1\. Any condition that, in the opinion of the investigator, contraindicates participation in this study.
  • Co-enrollment guidelines: Participants must be co-enrolled, planned for co-enrollment, or recently enrolled in a challenge study. Co-enrollment in other studies is restricted but may take place after study staff notification and only with approval of the principal investigator or designee.

Exclusion

    Key Trial Info

    Start Date :

    October 23 2023

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    June 2 2026

    Estimated Enrollment :

    1000 Patients enrolled

    Trial Details

    Trial ID

    NCT04772170

    Start Date

    October 23 2023

    End Date

    June 2 2026

    Last Update

    October 9 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    National Institutes of Health Clinical Center

    Bethesda, Maryland, United States, 20892

    Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies | DecenTrialz