Status:

COMPLETED

Effect of Amnion Membrane With and Without Taurine on GCF TNF α Level.

Lead Sponsor:

Maharishi Markendeswar University (Deemed to be University)

Conditions:

Periodontitis

Eligibility:

All Genders

29-60 years

Phase:

NA

Brief Summary

45 sites in 15 patients with periodontal pockets ≥ 5mm were selected. These selected sites were divided into 3 groups as Group A, B and C.

Detailed Description

Group A (Control): 15 sites received only SRP, Group B: 15 sites received SRP with subgingival placement of amnion membrane, Group C: 15 sites received SRP with subgingival placement of Amnion membran...

Eligibility Criteria

Inclusion

  • •Systemically healthy patients with sites showing probing depth (PD) ≥ 5mm, clinical attachment level (CAL) ≥ 4 mm, and vertical bone loss ≥ 3 mm on intraoral periapical radiographs with no history of periodontal therapy or use of antibiotics in the preceding 6 months

Exclusion

  • Any systemic disease that could influence the outcome of periodontal therapy.
  • Smokers, alcoholics \& patients with other adverse habits.
  • Pregnant or nursing women.
  • Any known allergy or hypersensitivity to any product used in the study.
  • Patients on long term systemic therapy (antibiotics, anti-inflammatory and any other).

Key Trial Info

Start Date :

December 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 13 2021

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT04772508

Start Date

December 1 2020

End Date

March 13 2021

Last Update

March 16 2021

Active Locations (1)

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1

Department of Periodontology, M.M. College of Dental Sciences and Research.

Ambāla, Haryana, India, 133207