Status:
COMPLETED
DNA Damage in Critically Ill COVID-19 Patients
Lead Sponsor:
University Hospital Hradec Kralove
Conditions:
Covid19
Organ Failure, Multiple
Eligibility:
All Genders
18+ years
Brief Summary
Critically ill patients with COVID-19 are exposed to high oxidative stress which is potential harm to the DNA. Peripheral lymphocytes' DNA will be investigated using the comet assay on changes in oxid...
Detailed Description
Data from hospital documentation will be recorded for all patients: demographic data, clinical data (Horowitz index, the necessity of pronation position, opening maneuvers, connection to ECMO, state o...
Eligibility Criteria
Inclusion
- critically ill adult patient admitted to ICU with positive RT-PCR test or bed-side antigen test on COVID-19 with signs and symptoms of organ failure
- informed consent
Exclusion
- rejection by the patient to sign an informed consent
Key Trial Info
Start Date :
November 23 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 28 2021
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT04772703
Start Date
November 23 2020
End Date
February 28 2021
Last Update
September 27 2022
Active Locations (1)
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1
University Hospital Hradec Kralove
Hradec Králové, Třebeš, Czechia, 50005