Status:
COMPLETED
Predictors of Adverse Left Ventricular Remodeling and Final Infarct Size After Primary Percutaneous Coronary Intervention for ST Elevation Myocardial Infarction: A Strain Analysis Study Using Echocardiography and Feature Tracking Cardiac Magnetic Resonance
Lead Sponsor:
Cairo University
Collaborating Sponsors:
Aswan Heart Centre
Conditions:
ST Elevation Myocardial Infarction
Remodeling, Left Ventricle
Eligibility:
All Genders
18-80 years
Brief Summary
ST-segment elevation myocardial infarction (STEMI) is one of the most important causes of death and disability around the world. The main goal in the management of acute myocardial infarction (AMI) i...
Detailed Description
The study will enroll 100 consecutive patients with acute STEMI presenting to Aswan Heart Centre catheterization-lab for primary PCI matching the selection criteria. Diagnosis of STEMI will be based u...
Eligibility Criteria
Inclusion
- STEMI with time from symptom onset of \<48 hours duration.
Exclusion
- I. Clinical exclusion criteria:
- STEMI patients receiving fibrinolytic therapy.
- Cardiogenic shock, clinical, hemodynamic, or electrical instability persisting after primary PCI.
- History of prior ST elevation myocardial infarction.
- Unsuccessful angiographic reperfusion (Thrombolysis In Myocardial Infarction \[TIMI\] flow grade \<2).
- II. Contraindications to CMR:
- Cerebral aneurysm clips
- Cardiovascular implanted electronic devices
- Electronic implant or device, eg, insulin pump or other infusion pump
- Cochlear or otologic implant
- Shunt (spinal or intraventricular)
- Tissue expander (eg, breast)
- Metallic foreign body, especially ocular
- Penile prosthesis.
- Patients with stage 4 or 5 chronic kidney disease (estimated glomerular filtration rate \<30 mL/min/1.73 m2)
- Known claustrophobia
- Known/possible pregnancy
Key Trial Info
Start Date :
March 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 31 2022
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04773652
Start Date
March 1 2021
End Date
August 31 2022
Last Update
February 8 2023
Active Locations (1)
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1
Aswan Heart Centre
Aswān, Egypt, 81511