Status:

UNKNOWN

Probiotic Supplementation in the Dysbiosis of Bowel Preparation

Lead Sponsor:

National Taiwan University Hospital

Conditions:

Microbial Colonization

Irritable Bowel Syndrome

Eligibility:

All Genders

20+ years

Phase:

NA

Brief Summary

Significant changes in gut microbiota was noted after the high-volume bowel preparation with PEG before colonoscopy. The dynamic changes were found to be short-term. However, the perturbation pattern ...

Detailed Description

Objectives: Colonoscopy is widely used for identification and treatment of colon polyps and intestinal symptoms. High-volume polyethylene glycol (PEG) bowel preparation prior to colonoscopy causes sig...

Eligibility Criteria

Inclusion

  • Adults age \>20
  • Undergoing colonofibroscopy (CFS) with PEG bowel preparation

Exclusion

  • Inadequate bowel preparation
  • Subjects with active cancer or IBD (inflammatory bowel disease)
  • Subjects with history of abdominal surgery (including stomach, gallbladder, pancreas, small bowel, large bowel)
  • Subjects who take medication related to gastrointestinal motility within 1 months
  • Subjects who take antibiotics or probiotics within 1 months
  • Subjects under pregnancy
  • Allergic or intolerance to the study medication
  • Refused to randomization

Key Trial Info

Start Date :

March 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2023

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT04774042

Start Date

March 1 2021

End Date

January 1 2023

Last Update

February 26 2021

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