Status:

COMPLETED

Preliminary Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair

Lead Sponsor:

Concentric Analgesics

Conditions:

Postsurgical Pain

Eligibility:

All Genders

18-80 years

Phase:

PHASE1

PHASE2

Brief Summary

A Three-Part, Phase 1/2, Randomized, Double-blind, Placebo-Controlled, Adaptive Safety, Pharmacokinetics, and Preliminary Efficacy Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia...

Eligibility Criteria

Inclusion

  • Scheduled elective, primary, open laparotomy with VHR, with retromuscular, preperitoneal mesh placement, with midline fascial reconstruction
  • ASA physical class 1, 2, or 3
  • BMI \</= 40 kg/m2
  • Aged 18-80 years old

Exclusion

  • Concurrent condition requiring analgesic treatment during study period
  • Opioid tolerant
  • Known allergy to capsaicin or other study medication
  • Use of prohibited medications

Key Trial Info

Start Date :

September 9 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 15 2021

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT04774328

Start Date

September 9 2020

End Date

June 15 2021

Last Update

September 14 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

First Surgical Hospital

Houston, Texas, United States, 77004