Status:

COMPLETED

Antibody Response to COVID-19 Vaccines in Liver Disease Patients

Lead Sponsor:

Humanity & Health Medical Group Limited

Conditions:

Chronic Liver Disease

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Currently the Pfizer-Biontech (mRNA), Sinovac (inactivated virus) and Astrazeneca-Oxford (adenovirus-vector) COVID-19 vaccines are available for vaccination in HK. The American Association of Liver Di...

Eligibility Criteria

Inclusion

  • Subjects with chronic liver disease (CLD) at the Humanity and Health Medical Group and eligible for the HK government vaccination programme;
  • Able to understand and sign informed consent.;
  • Underlying CLD- defined as patients with chronic hepatitis B or C infections, liver cirrhosis, metabolic associated liver disease, hepatocellular carcinoma, alcoholic liver disease, autoimmune hepatitis, hemochrombtosis.

Exclusion

  • Patients contraindicated for the COVID -19 Vaccination Program due to uncontrolled co-morbitities;
  • Past allergies to other vaccines;
  • Pregnant subjects.

Key Trial Info

Start Date :

May 21 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 30 2023

Estimated Enrollment :

232 Patients enrolled

Trial Details

Trial ID

NCT04775069

Start Date

May 21 2021

End Date

September 30 2023

Last Update

October 4 2023

Active Locations (1)

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Humanity & Health Medical Group Limited

Hong Kong, Hong Kong