Status:
RECRUITING
STEMI Treatment Optimization by Ischemic Postconditioning and IVUS Guidance
Lead Sponsor:
Thomas Engstrom
Conditions:
ST Elevation Myocardial Infarction
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of is study is to investigate whether ischemic postconditioning (iPOST) and intravascular ultrasound-guided (IVUS) percutaneous coronary intervention (PCI) improve the clinical outcome of ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Age ≥18 years
- Acute onset of chest pain with \<12 hours duration
- STEMI as characterized by 2 mm ST elevation in 2 or more V1 through V4 leads or presumed new left bundle branch block with minimum of 1 mm concordant ST elevation or 1 mV ST-segment elevation in the limb lead (II, III and aVF, I, aVL) and V4-V6 or ST depression in 2 or more V1 through V4 leads indicating posterior AMI.
- Exclusion Criteria (iPOST2):
- Pre-PCI TIMI flow 0 or 1 Potential pregnancy Inability to provide informed consent Unwillingness to consent Unavoidable to use thrombectomy Spontaneous coronary artery dissection Time from symptoms onset to PPCI \> 12 hours Culprit in bypass graft Other reason for not including the patient
- Exclusion Criteria (iSTEMI):
- Potential pregnancy Inability to understand information in order to provide informed consent Unwillingness to consent Spontaneous coronary artery dissection Time from symptoms inset to PPCI \> 12 hours Culprit in bypass graft Other reason
Exclusion
Key Trial Info
Start Date :
April 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2031
Estimated Enrollment :
2500 Patients enrolled
Trial Details
Trial ID
NCT04775914
Start Date
April 1 2021
End Date
February 1 2031
Last Update
December 19 2023
Active Locations (1)
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1
Heart Center, Rigshospitalet
Copenhagen, Capital Region, Denmark, 2100