Status:
COMPLETED
Effect of Self-Assembling Peptides on the Progression of Non-Cavitated Proximal Caries
Lead Sponsor:
Izmir Katip Celebi University
Conditions:
Proximal Caries
Eligibility:
All Genders
7-13 years
Phase:
NA
Brief Summary
The aim of this randomized controlled, double-blinded, split-mouth clinical trial was to evaluate the efficacy of self-assembling peptide P11-4 solution (Curodont™ Repair) with fluoride varnish on the...
Detailed Description
First, the subjects were randomly allocated to three main groups with 50 individuals in each. Then the carious lesions belonging to each subject were randomly assigned to two subgroups based on differ...
Eligibility Criteria
Inclusion
- Children who had two permanent molars with non-cavitated proximal carious lesions that included one in the right jaw and the other one in the left jaw, and in contact with neighboring teeth,
- Non-cavitated proximal carious lesions which is radiographically extending into either the outer half of the enamel (E1), the inner half of the enamel (E2) or the outer third of the dentin (D1),
- Children who had not any systemic disease that prevents the application,
- Cooperative children who allowed to radiographic examinations and clinical applications.
Exclusion
- There is caries/restoration on the different surface of the tooth to be treated,
- There is caries/restoration on the contact surface of the tooth adjacent to the tooth to be treated,
- Non-cavitated proximal carious lesions which is radiographically extending into the middle third of the dentin (D2) or the inner third of the dentin (D3),
- There is cavitation on the proximal surface of the tooth to be treated,
- Non-cooperative children who had not allow to radiographic examinations and clinical applications,
- Children and parents who denied the participation in the follow-up appointments.
Key Trial Info
Start Date :
October 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 8 2021
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT04776785
Start Date
October 1 2019
End Date
January 8 2021
Last Update
March 12 2021
Active Locations (2)
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1
Izmir Katip Celebi Uni.
Izmir, Turkey (Türkiye)
2
Izmir Katip Celebi University
Izmir, Turkey (Türkiye)