Status:
UNKNOWN
The Effects of Iontophoresed Vasoactive Drugs on Cutaneus Blood Flow
Lead Sponsor:
University Hospital, Linkoeping
Conditions:
Cardiovascular Diseases
Vascular Diseases
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
Many acute and chronical medical conditions, such as, shock, sepsis, diabetes, hypertonia, and cardiovascular disease are associated with a perturbated or lost ability of regulating the diameter of th...
Detailed Description
A non-randomised study to investigate how 6 different vasoactive substances administrated in 5 different concentrations, and with repeated administration affect the cutaneous superficial vessels. The ...
Eligibility Criteria
Inclusion
- Healthy
- No ongoing medication
- No skin disease or other skin afflictions
- Informed, voluntary participation
Exclusion
- Ongoing medication (contraceptives excluded)
- Hypertonia, skin disease or skin afflictions, cardiovascular disease, pregnancy
- Damaged skin, bruises, scar tissue or tattoos on the skin of the forearms
- Smoking (6 months prior to study onset, or more than 100 cigarettes in life)
- Snus (6 months prior to study onset)
- Use of nicotine products (gum, patch, et cetera) 6 months prior to study onset
- Blood pressure above 140/90
- Coffee, tea, alcohol or strenuous physical activity on the day of the study
- Not fasting for 2 hours prior onset of the study
Key Trial Info
Start Date :
April 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2021
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT04777383
Start Date
April 1 2019
End Date
December 31 2021
Last Update
March 2 2021
Active Locations (1)
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1
University Hospital Linköping
Linköping, Östergötland County, Sweden, 58185