Status:
COMPLETED
Neuroscience of Charles Bonnet Syndrome
Lead Sponsor:
University of Oxford
Conditions:
Charles Bonnet Syndrome
Eligibility:
All Genders
18-70 years
Brief Summary
Charles Bonnet Syndrome (CBS) is a condition in which people experience complex visual hallucinations, such as 'Acrobats balancing on bicycles' or 'Spiders crossing meals'. The condition usually occur...
Detailed Description
Charles Bonnet Syndrome (CBS) has been reported in people with visual impairment, and is surprisingly common with an estimated prevalence of 10-34% of low vision patients from local audits. It consist...
Eligibility Criteria
Inclusion
- Participant is willing \& able to give informed consent for participation in the study.
- Male or female, aged 18 - 70 years.
- Reduced vision.
Exclusion
- Pre-existing amblyopia or squint.
- Insufficient understanding of written and verbal English to complete safety screening questionnaires.
- Pregnancy or trying to conceive.
- Other neurological problems which may confound the results, e.g. diagnosis of Parkinsons.
- Contraindication to MRI e.g. claustrophobia, presence of metallic implants, a pacemaker, recent surgery etc.
- MR Spectroscopy contraindications e.g. use of antidepressants or antipsychotic medication, frequent cigarette and alcohol consumption. This is defined as no more than one cigarette per day within the past 3 months, and no alcohol use within 3 days prior to scanning.
Key Trial Info
Start Date :
September 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 20 2023
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT04777630
Start Date
September 1 2021
End Date
December 20 2023
Last Update
May 9 2024
Active Locations (2)
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1
Vision and Eye Research Institute
Cambridge, United Kingdom
2
Wellcome Centre for Integrative Neuroimaging
Oxford, United Kingdom, OX3 9DU