Status:
UNKNOWN
Preoperative Abdominal Enhanced CT, 18F-FDG PET/CT and 68Ga-FAPI PET/CT in Peritoneal Carcinomatosis of Gastric Cancer
Lead Sponsor:
Fujian Medical University
Conditions:
Enhanced CT
18F-FDG PET/CT
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
This study aims to explore the value of 68Ga-FAPI PET/CT in the diagnosis of gastric cancer peritoneal carcinomatosis in high-risk patients compared with conventional abdominal enhanced CT and 18F-FDG...
Detailed Description
After being informed about the study and potential risks, all patients giving written informed consent will receive 68Ga-FAPI PET/CT on the 2nd day to 1st week of 18F-FDG PET/CT. On PET/CT, omentum, p...
Eligibility Criteria
Inclusion
- Age from 18 to 75 years
- Primary gastric adenocarcinoma (papillary, tubular, mucinous, signet ring cell, or poorly differentiated) confirmed pathologically by endoscopic biopsy
- The clinical tumor stage before PET/CT scan was evaluated as cT4/N+/M0-1, according to the American Joint Committee on Cancer (AJCC) Cancer Staging Manual Eighth Edition
- Performance status of 0 or 1 on Eastern Cooperative Oncology Group scale (ECOG)
- American Society of Anesthesiology score (ASA) class I, II, or III
- Written informed consent
Exclusion
- Women during pregnancy or breast-feeding
- Severe mental disorder
- History of previous abdominal inflammatory diseases (such as peritonitis, pancreatitis, cholecystitis, inflammatory bowel disease)
- History of unstable angina or myocardial infarction within past six months
- History of cerebrovascular accident within past six months
- History of continuous systematic administration of corticosteroids within one month
- Emergency surgery due to complication (bleeding, obstruction or perforation) caused by gastric cancer
- Forced expiratory volume in 1 second (FEV1)\<50% of predicted values
- History of allergy to tracer agents of PET/CT
- History of allergy to contrast agents of CT
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2023
Estimated Enrollment :
72 Patients enrolled
Trial Details
Trial ID
NCT04778345
Start Date
March 1 2021
End Date
March 1 2023
Last Update
March 3 2021
Active Locations (1)
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1
Department of Gastric Surgery
Fuzhou, Fujian, China