Status:
UNKNOWN
Role of Ultrasound Assessment of Parasternal Intercostal Muscle Thickness During Weaning From Mechanical Ventilation
Lead Sponsor:
Wesameldin Abelrahman Soltan
Conditions:
Parasternal Intercostal Muscle Thickness
Weaning From Mechanical Ventilation
Eligibility:
All Genders
18-80 years
Brief Summary
Assessment of the the parasternal intercostal muscles thickness by the ultrasonography as a weaning predictor of the mechanically ventilated patients
Detailed Description
impact of parasternal muscle thickness on the weaning process of the mechanically ventilated patients in ICU
Eligibility Criteria
Inclusion
- Any patient invasively mechanically ventilated at least 24 hours on a pressure support mode who is clinically stable and ready to undergo a spontaneous breathing trial.
- All patients will be:
- Alert.
- Afebrile.
- Adequate cough with absence of excessive tracheobronchial secretion.
- Fraction of inspired oxygen (FIO2) of \<50%.
- PEEP ≤8 cmH2O.
- PaO2/FiO2 \> 150.
- pH ≥7.35 and ≤7.45.
- Respiratory rate (RR) ≤35 breaths/min.
- Hemodynamically stable in the absence of vasopressors.
- Stable metabolic and endocrinal status.
- Euglycemic state.
- Adequate mentation (no sedation or stable neurologic patient).
Exclusion
- Diaphragmatic paralysis (detected by ultrasonography).Patients\&Methods. 6
- Pregnant women.
- Age: \>= 18 years.
- Surgical dressings over measurement point which would preclude ultrasound exam.
- Underweight patients (Body mass index \<18.5 kg/m2).
- Morbidly obese patient (Body mass index ≥ 40 kg/m2).
- Primary neuro-muscular diseases.
- Central coditions with depressed central respiratory drive (encephalitis, and brainstem haemorrhage/ischaemia).
- Repiratory conditions with reduced pulmonary compliance (interstitial lung disease, pulmonary hemorrhage, and diffuse pulmonary infiltrates) or reduced chest wall compliance (kyphoscoliosis).
- Cardiac conditions with high risk of weaning induced pulmonary edema (congestive heart failure, cyanotic heart diease, pulmonary hypertension, and ischemic heart diease).
- Addict patients.
- Patients with psychiatric disease.
Key Trial Info
Start Date :
June 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2021
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04779463
Start Date
June 1 2020
End Date
April 1 2021
Last Update
March 3 2021
Active Locations (1)
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1
Faculty of Medicine - Menoufia University
Shibīn al Kawm, Menoufia, Egypt, 32511