Status:
COMPLETED
Comparison of Liberal and Restrictive Fluid Management on the Endothelial Glycocalyx in Radical Cystectomy
Lead Sponsor:
Istanbul University
Conditions:
Fluid Retention Tissue
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The aim of this study is to compare the effect of the liberal and restrictive fluid treatments which are routinely performed in major urological surgeries in the perioperative period on ANP release an...
Detailed Description
There is no strong evidence about the optimal fluid resuscitation for the patients undergoing major surgeries. Avoiding excess fluid resuscitation in the perioperative period is essential for reducing...
Eligibility Criteria
Inclusion
- ASA (The American Society of Anesthesiologists) status I-II-III patients
- Cases undergoing major urological surgery
- Cases for invasive artery monitoring and central venous catheterization
- Patients receiving general anesthesia
- Volunteering to participate in the study
Exclusion
- Coagulopathy
- Patients with severe heart, kidney and liver dysfunction (EF \<35% and / or GFR \<30, Cre:\> 2.5 and / or impaired liver function tests)
Key Trial Info
Start Date :
March 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2021
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT04780490
Start Date
March 1 2018
End Date
April 1 2021
Last Update
March 29 2022
Active Locations (1)
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1
Istanbul University
Istanbul, Turkey (Türkiye), 34093