Status:
COMPLETED
Staphylococcus Aureus Caught in Action at the Site of Infection
Lead Sponsor:
University Hospital, Basel, Switzerland
Conditions:
Staphylococcus (S.) Aureus Infection
Eligibility:
All Genders
18+ years
Brief Summary
This study is to obtain a comprehensive view of S. aureus adaptations in the infected human host and (i) to improve the understanding of the interface between antibiotic therapy, resistance developmen...
Detailed Description
Staphylococcus (S.) aureus is notorious for its ability to develop resistance. This study is to obtain a comprehensive view of S. aureus adaptations in the infected human host and (i) to improve the u...
Eligibility Criteria
Inclusion
- Inclusion criteria for patients:
- In collaboration with the orthopedic surgeons, patients with probable or proven S. aureus infections will be identified who will routinely undergo diagnostic and surgical procedures:
- Inclusion criteria for healthy participants:
- Healthy control group should be generally well-being
- Exclusion criteria for patients and for healthy participants:
- Pregnancy: Pregnant or lactating women will be excluded (urinary pregnancy test will be performed in women of childbearing age)
- General health condition: Current or recurrent disease that could cause complications that may affect the study or may set the patient at risk
- Diseases/ Illness: Psychiatric or other mental disorders which in the opinion of the investigator may probably affect the full understanding of the study (including signs of dementia)
- Language: Insufficient knowledge of german language to understand the procedure and rationale of the research question
- Vulnerability: Individuals whose willingness to volunteer in the research project may be unduly influenced by the expectation, whether justified or not, of benefits associated with participation, such as members of a group with a direct hierarchical structure (refer to ICH Guidelines E6 (R1) for GCP, 1.61)
Exclusion
Key Trial Info
Start Date :
June 6 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 23 2020
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04781569
Start Date
June 6 2017
End Date
November 23 2020
Last Update
June 3 2021
Active Locations (1)
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1
University Hospital Basel
Basel, Switzerland, 4031