Status:

RECRUITING

Multimodal Brain Imaging of the Neural Effects of Methylphenidate in Patients With ADHD

Lead Sponsor:

Johns Hopkins University

Collaborating Sponsors:

National Institutes of Health (NIH)

Conditions:

ADHD - Combined Type

Eligibility:

All Genders

6-40 years

Phase:

PHASE4

Brief Summary

The investigators' goal is to develop neuroimaging biomarkers to predict response to treatment with methylphenidate, which then can be used in the development of novel pharmacological treatments for a...

Eligibility Criteria

Inclusion

  • right handed

Exclusion

  • pregnant or breast feeding
  • past or current neurological disorder
  • non-ADHD cause of cognitive impairment
  • uncontrolled medical disorder
  • head trauma with loss of consciousness in the last year or any evidence of functional impairment due to and persisting after head trauma
  • having an adverse reaction to methylphenidate, or other stimulant medication
  • having a contraindication to MRI
  • current smoking

Key Trial Info

Start Date :

July 27 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 30 2029

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04781972

Start Date

July 27 2021

End Date

April 30 2029

Last Update

October 16 2025

Active Locations (1)

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1

Johns Hopkins School of Medicine

Baltimore, Maryland, United States, 21205