Status:
UNKNOWN
Effect of Traditional Chinese Medicine on Basic Tear Secretion and Tear Cytokines in Patients With Dry Eye Disease
Lead Sponsor:
China Medical University Hospital
Conditions:
Dry Eye Disease
Dry Eye Syndromes
Eligibility:
All Genders
20-75 years
Phase:
PHASE2
Brief Summary
This is a single center, randomized, single-blind, controlled pilot study of CJDHW plus JWXYS as a complementary therapy to treat dry eye disease during a 12-week period. The investigators intend to e...
Detailed Description
Dry eye disease (DED) is a chronic inflammatory disease. In severe cases, it may cause corneal ulcers, blurred vision, and even blindness. The prevalence of DED is about 30% in Taiwan. With the popula...
Eligibility Criteria
Inclusion
- Age between 20 and 75 years.
- A confirmed diagnosis of DED by ophthalmologists.
- Willing to sign informed consent form.
Exclusion
- With autoimmune diseases.
- Pregnant or lactating.
- Underwent transplant surgery and got graft-versus-host disease in the past.
- With eye infection, inflammation, trauma, or underwent eye surgery in the past three months.
- Underwent dry eye intense pulse light treatment in the past three months.
- Underwent other treatments including TCM drugs or acupuncture in the past month or during the trial.
- Persistent in taking diuretics, antidepressant, antihistamines and anticholinergics.
- Combined treatment with autologous serum, cyclosporine or steroid eye drops during the trial.
- Took fish oil or vitamin D during the trial.
Key Trial Info
Start Date :
March 16 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2022
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04785261
Start Date
March 16 2021
End Date
May 31 2022
Last Update
December 6 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
China Medical University Hospital
Taichung, Taiwan, 404332