Status:

WITHDRAWN

Food or Supplemental Lutein Absorption

Lead Sponsor:

The University of Queensland

Conditions:

Macula Lutea Opacity

Eligibility:

All Genders

18-40 years

Phase:

PHASE1

Brief Summary

The aim of this study is to investigate in healthy adults, 18-40 years of age, how the absorption of 5 mg of L differs between consumption as a supplement, blended foods, and whole food equivalent of ...

Detailed Description

The absorption the macular carotenoids has shown variability between different supplements, and food sources such as egg and spinach. Investigation of the absorption of different forms of food (e.g. c...

Eligibility Criteria

Inclusion

  • Male and females 18 to 40 years.
  • Generally healthy.
  • No participant reported history of clinically significant medical conditions including, but not limited to, cardiovascular, neurological, psychiatric, renal, immunological, endocrine (including uncontrolled diabetes or thyroid disease) or haematological abnormalities that are uncontrolled.
  • Non-smoker.
  • English language proficiency

Exclusion

  • Participant reported diagnosis of serious ocular conditions (e.g. cataracts, glaucoma, diabetic retinopathy, retinitis pigmentosa, Stagardt's disease)
  • Participant reported diagnosis, or current treatment of age-related macular degeneration.
  • Participant reported diagnosis of epilepsy.
  • Participant aversion, intolerance or allergy to study foods to be consumed (spinach, ginger, lemon, apple, flaxseeds)
  • A female currently pregnant or trying to fall pregnant.
  • Current or past smoker (within last 12 months).
  • Under 18 or over 40 years of age.
  • Currently taking a lutein supplement or consuming large amounts of foods containing lutein on a regular basis (\>3 days per week).

Key Trial Info

Start Date :

June 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2021

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04786392

Start Date

June 1 2021

End Date

June 1 2021

Last Update

July 12 2021

Active Locations (1)

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1

School of Human Movement and Nutrition Sciences, The University of Queensland

Saint Lucia, Queensland, Australia, 4067