Status:
UNKNOWN
COVID-19 Infection and Epithelial Cell Markers
Lead Sponsor:
McMaster University
Conditions:
Asthma
Covid19
Eligibility:
All Genders
18+ years
Brief Summary
To assess if TSLP expression by airway epithelial cells following COVID-19 infection regulates viral load and disease severity.
Detailed Description
The study aim is to determine the relationship between COVID-19 infection and epithelial cell expression of TSLP. Two cohorts will be used. Cohort One will include 100 hospitalized patients with Covid...
Eligibility Criteria
Inclusion
- Age 18 years and above;
- Able to give informed consent;
- Clinically tested for SARS-CoV-2 (as completed by standard laboratory testing e.g. RT-PCR) and with a positive result and clinical features in keeping with COVID-19 illness. The control group will be patients with a negative RT-PCR COVID-19 test and without any clinical features to suggest COVID-19 illness. In addition, the control group should have NO known or current features of respiratory infection, COPD, asthma, interstitial lung disease, other respiratory inflammatory conditions or lung cancer.
- Able to provide a breath sample (as based on clinical judgement).
Exclusion
- \- none
Key Trial Info
Start Date :
February 14 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 1 2022
Estimated Enrollment :
235 Patients enrolled
Trial Details
Trial ID
NCT04787588
Start Date
February 14 2021
End Date
February 1 2022
Last Update
March 8 2021
Active Locations (1)
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1
McMaster Cardio-Respiratory Research Lab
Hamilton, Ontario, Canada, L8N 3Z5