Status:
COMPLETED
Insight Into New Brown Adipose Tissue Activators.
Lead Sponsor:
Medical University of Bialystok
Conditions:
Adiposity
Metabolic Complication
Eligibility:
MALE
20-43 years
Brief Summary
The general purpose of the study was to provide new information about the role of macronutrients intake, metabolomics, proteomics and microRNA on BAT activation. The invesigator evaluated BAT activit...
Detailed Description
In detail, the main objectives of this study was to measure the influence of biological molecules of such fields: genomics, transcriptomics metabolomics and protemics and its relationship on BAT activ...
Eligibility Criteria
Inclusion
- Inclusion criteria to the group 1 (healthy males) N=20:
- BMI \<25 kg/m2;
- RR\<140/90mmHg;
- age 20-30/40 years
- fasting glycemia \<100mg/dl; 2h-OGTT \<140mg/dl;
- no chronic disease
- Inclusion criteria to the group 2 ( overweight/obese males) N=20:
- Blood pressure \< 140/90 mmHg (well controlled by inh ACE; no beta-blockers)
- No chronic disease
- BMI \> 25 \<35kg/m²
- fasting glycemia \<100mg/dl; 2h-OGTT \<140mg/dl;
Exclusion
- Any drug use: beta-blokers, statins, glucocorticoids drugs, hypertension drugs;
- hypertension;
- cancer;
- hormonal disorders;
- Inflammation process
- Smoking
- Claustrophobia
Key Trial Info
Start Date :
October 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 24 2018
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04787952
Start Date
October 1 2016
End Date
February 24 2018
Last Update
March 10 2021
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