Status:

UNKNOWN

The Effects of Preoperative Bevacizumab on Perioperative Complications

Lead Sponsor:

Second Affiliated Hospital, School of Medicine, Zhejiang University

Conditions:

Colorectal Cancer

Lung Cancer

Eligibility:

All Genders

18-90 years

Brief Summary

This is a nationwide multicenter,retrospective,observational real-world study. 1. To assess the risk of perioperative complications in patients with tumor who received bevacizumab prior to unexpected...

Detailed Description

Avastin (bevacizumab) is a recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor(VEGF) in in vitro and in vivo ass...

Eligibility Criteria

Inclusion

  • Patients with colorectal cancer and lung cancer who underwent unexpected operation from 01 Jan 2010 to 31 Dec 2019, and received bevacizumab within 6 weeks (including 6 weeks) before operation;
  • Patients aged 18-90 years old;
  • Complete clinical data related to important indicators, including preoperative baseline data, surgical information and perioperative prognosis information.

Exclusion

  • Patients who used anti-angiogenic agents other than bevacizumab within 6 weeks prior to unexcepted operation.

Key Trial Info

Start Date :

April 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 31 2021

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04788381

Start Date

April 1 2021

End Date

July 31 2021

Last Update

March 9 2021

Active Locations (1)

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The Second Affiliated Hospital Zhejiang University School of Medicine

Hangzhou, Zhejiang, China, 0571