Status:
ENROLLING_BY_INVITATION
Auditory Stimulation Effects on Sleep and Memory in Patients With Epilepsy
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Epilepsy
Eligibility:
All Genders
12-65 years
Phase:
NA
Brief Summary
This study will investigate the role of coordinated brain rhythms during sleep in memory consolidation and determine whether playing precisely timed brief bursts of noise can enhance these rhythms and...
Detailed Description
The investigators will test the hypotheses that coordinated brain rhythms during nonrapid eye movement sleep are associated with memory consolidation and can be enhanced with auditory stimulation (pla...
Eligibility Criteria
Inclusion
- Inpatients with epilepsy
- Aged 12-65
- Undergoing clinically indicated continuous scalp and intracranial EEG monitoring with implanted hippocampal electrodes
- Fluent in English
- Able to give informed consent/assent (for minors aged 12-17 or adults with an appointed guardian)
Exclusion
- Intellectual disability impairing ability to perform task
- Motor problems that preclude finger tapping task
- Previous surgery anticipated to disrupt coordination of sleep oscillations in the circuitry of interest
Key Trial Info
Start Date :
January 21 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 31 2026
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT04788628
Start Date
January 21 2021
End Date
March 31 2026
Last Update
November 17 2025
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114