Status:
COMPLETED
No Monitoring of Post-filter Ionized Calcium in Regional Citrate Anticoagulation
Lead Sponsor:
Chulalongkorn University
Conditions:
Regional Citrate Anticoagulation
Ionized Calcium
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Do no monitor of post-circuit ionized calcium affact the filter life time of continueous renal replacement therapy with regional citrate anticoagulation circuit? A randomized control trial
Detailed Description
Regional citrate anticoagulation is the gold standard of anticoagulation in patient receiving CRRT. In RCA circuit, there was a monitoring of pre-filter (systemic) ionized calcium and post-filter (cir...
Eligibility Criteria
Inclusion
- Age older than 18 years old and admission in an ICU
- Indication for CRRT
- regional citrate anticoagulation
Exclusion
- Acute liver failure defined as AST or ALT \> 5X UNL or TB/DB \> 5X UNL or evidence of cirrhosis
- Severe persistent lactic acidosis (lactate persist \> 8 mg/dL consecutively within 6 hours)
- Receiving heparin anticoagulation
- Severe alkalosis (pH\>7.55) or acidosis (pH\<7.1)
- History of renal allograft
- Known pregnancy
- Patient is moribund with expected death within 24 hr
- Deficiency of ionzed calcium (Cation \< 0.8 mmol/L)
Key Trial Info
Start Date :
April 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 15 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04792424
Start Date
April 1 2021
End Date
June 15 2022
Last Update
November 14 2022
Active Locations (1)
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1
Chulalongkorn university
Bangkok, Thailand, 10330